Studies on echinococcosis. XXV. Anthelmintic action of drugs on larval Echinococcus multilocularis in vitro.

In vitro activities of benzimidazoles against Echinococcus multilocularis metacestodes.

Alveolar echinococcosis, caused by the larval (metacestode) stage of the tapeworm Echinococcus multilocularis, is a lethal parasitosis of the liver prevalent in the Northern Hemisphere. For chemotherapy the benzimidazole derivatives mebendazole and albendazole were introduced, and their use has resulted in a significant improvement in the survival rates. However, data from experiments with anim...

Studies on echinococcosis. XVI. Effects of drugs upon scolices and daughter cysts of Echinococcus multilocularis in vitro.

Studies on echinococcosis XX. Preliminary observations of the in vivo cultivation of larval tissue of Echinococcus multilocularis in culture-chamber of porous membrane.

Molecular and immunological diagnosis of echinococcosis.

Echinococcosis is an infectious disease of humans caused by the larval (metacestode) stage of the cestode species Echinococcus granulosus (cystic echinococcosis or hydatid disease) or Echinococcus multilocularis (alveolar echinococcosis or alveolar hydatid disease). Clinical manifestations depend primarily on localization and size of hepatic lesions and may include hepatomegaly, obstructive jau...

Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern.

Echinococcosis in humans is a zoonotic infection caused by larval stages (metacestodes) of cestode species of the genus Echinococcus. Cystic echinococcosis (CE) is caused by Echinococcus granulosus, alveolar echinococcosis (AE) is caused by E. multilocularis, and polycystic forms are caused by either E. vogeli or E. oligarthrus. In untreated cases, AE has a high mortality rate. Although control...